Season 5 of the series was premiered on September 24, 2008. This season of the series is supposed to have nineteen episodes, but till date only twelve episodes have been aired. The fifth season started from where the fourth season had ended. In the first episode of the season we find the team investigating the death of a woman named Lauren Salinas, whose death is linked to the bank robbery. After the investigations the team comes to know that Lauren was a friend of Flack’s sister, Samantha. Though Mac managed to escape from the hands of the robber, but there are others who are being killed. In order to stop the killings the team must quickly find the robber before he is able to get away with many more killings. In the next episode of the series, after a number of deaths start taking place in the New York City Library.
| No. | Episode | Air date | ||
| 1 | Veritas | 9/24/2008 | ||
| 2 | Page Turner | 10/1/2008 | ||
| 3 | Turbulence | 10/8/2008 | ||
| 4 | Sex, Lies, And Silicone | 10/22/2008 | ||
| 5 | The Cost of Living | 10/29/2008 | ||
| 6 | Enough | 11/5/2008 | ||
| 7 | Dead Inside | 11/12/2008 | ||
| 8 | My Name is Mac Taylor | 11/19/2008 | ||
| 9 | The Box | 11/26/2008 | ||
| 10 | The Triangle | 12/10/2008 | ||
| 11 | Forbidden Fruit | 12/17/2008 | ||
| 12 | Help | 1/14/2009 | ||
| 13 | Rush To Judgment | 1/21/2009 | ||
| 14 | She’s Not There | 2/11/2009 | ||
| 15 | The Party’s Over | 2/18/2009 | ||
| 16 | No Good Deed | 2/25/2009 | ||
| 17 | Green Piece | 3/11/2009 | ||
| 18 | Point of No Return | 3/18/2009 | ||
| 19 | Communication Breakdown | 0/0/0 | ||
| 20 | Prey | 0/0/0 | ||
| 21 | The past, present and murder | 0/0/0 | ||
| 22 | Yahrzeit | 0/0/0 | ||
| 23 | Greater good | 0/0/0 | ||
| 24 | Grounds for Deception | 5/13/2009 | ||
| 25 | Pay Up | 5/20/2009 |